New NDM-1 genetically modified gram-negative bacteria superbug threat

An enzyme responsible for a new class of super bacteria with a genetically modified defense - NDM-1 - which makes the bacteria carrying it immune to most or all known anti-biotics has infection experts alarmed. The multi-drug resistance facilitated by the gene New Delhi metallo-beta-lactamase or NDM-1 can easily jump from one strain of bacteria to another, possibly creating a pandemic of resistant infections.

The bacteria with the modified genetics have been found world-wide.

So far all the bugs which have this extra-chromosomal DNA are gram-negative, which are a more complex bacteria with a double cell wall. Today, most pharmaceutical companies are not making drugs to combat these types of bacteria because the gram-negative, double-cell walled bugs are more difficult to combat and kill.  For gram-negative bacteria, the pipeline of new and developing antibiotics and drugs is essentially dry.

QuorumEx's first product, Topic-QX has been shown to be highly effective in the disruption of gram-negative bacterial quorum sensing.

See Quorumex.com/news for more information.

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Scientists find superbugs in Delhi drinking water

Reuters is now reporting that the same superbug is now showing up in New Dehli's water systems.

A gene that makes bugs highly resistant to almost all known antibiotics has been found in bacteria in water supplies in New Delhi used by local people for drinking, washing and cooking, scientists said on Thursday.

 

"We are at a critical point in time where antibiotic resistance is reaching unprecedented levels," said Zsuzsanna Jakab, the WHO's regional director for Europe.

"Given the growth of travel and trade in Europe and across the world, people should be aware that until all countries tackle this, no country alone can be safe."

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